Absolutely , I’ve been on Opzalura& light therapy 3 times /week. I can only tolerate Opzalura once a day as I am sensitive. Before Opzalura was available I was already taking the oral form, Xeljanz XR 11 mg 3 times per week,Been using Opzalura when it first became available . When administered together the results are excellent!! I have 85-90 percent repigmentation. Most successful on hands, arms, face,under arms,legs are very difficult to repigment,, when I only use Opzalura, like on vacation, the vitiligo itches& spreads! Stress triggers it to spread, as does eating pro inflammatory foods. !!!