Hello Kim6,

Pray this finds you having a good day. So sorry to hear you have new spots since taking this medication. I take Meloxicam when needed and I haven’t seen any new spots. That being said, my spots have been active which is not the norm for me in Spring/Summer. Try to have a good day on purpose.

Kim6, hello and I hope you're doing well. I'm having a wonderful day! In response to your question; there is no definitive evidence suggesting that meloxicam (Mobic) directly causes vitiligo.
However, some research indicates a potential connection between meloxicam and phototoxicity, which could indirectly contribute to or exacerbate vitiligo in predisposed individuals.
Here's why this possibility exists:
Phototoxicity: Meloxicam has been shown to be phototoxic, meaning it can make the skin more sensitive to sunlight.
Melanin and Skin Accumulation: Meloxicam, due to its affinity for melanin, may accumulate in skin tissues, increasing the risk of phototoxic effects when exposed to sunlight.
Melanocyte Damage: Photosensitivity and oxidative stress induced by certain medications, including NSAIDs like meloxicam, can lead to damage to melanocytes, the cells responsible for producing skin pigment, potentially triggering or worsening vitiligo.
Important considerations
Drug-induced vitiligo: Vitiligo can be a side effect of certain medications, particularly immunomodulatory drugs and those used in cancer therapy.
Individual predisposition: People with a predisposition to vitiligo may be more susceptible to drug-induced depigmentation.
If you are concerned about a potential link between meloxicam and vitiligo, it's crucial to consult your dermatologist for proper diagnosis and guidance.
While meloxicam is not explicitly listed as a direct cause of vitiligo, its phototoxic nature and potential for interaction with melanin suggest a possible, albeit indirect, role in triggering or worsening vitiligo, particularly in sensitive individuals or with prolonged exposure to sunlight.
It is important to discuss any concerns with your dermatologist and follow their guidance regarding medication and potential side effects. 😃

Thanks everyone:) I really do not take any medications except ibuprofen on occasion. It never occurred to me that some meds might interact, I became curious if any other meds exacerbate vitiligo. Guess folks haven't experienced it. That is good to know!